e antigen in acute hepatitis B.

Occurrence of e antigen in acute hepatitis B.

The occurrence of e antigen in 44 patients with acute hepatitis B was studied in order to determine if e was related to the outcome of the illness. In 13.6% of cases e was detected, and in none of these did the carrier state develop. The HBsAg carrier state developed in 4.6% of the patients and in none of these was e antigen detected. Anti-e was detected in only three cases. Only in the very ea...

Expression of Hepatitis B Virus Core Antigen in Native and Fusion Forms in E. coli

DNA coding for the core antigen from hepatitis B Virus (HBcAg) was amplified, cloned and propagated in E. coli. The core protein was expressed in E. coli and the product was readily detected by Western blot. This protein can be used as a diagnostic material in serum screening tests. To increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

hepatitis b e antigen-negative chronic hepatitis b

Role of Hepatitis B Virus Surface Antigen Quantification in E Antigen Negative Chronic Hepatitis B Infection

Background/Aim: Hepatitis B surface antigen(HBsAg) is routinely detected qualitatively in Hepatitis B Virus(HBV) infection where its persistence beyond 6 months defines chronic hepatitis B(CHB) infection. Hepatitis B e antigen (HBeAg) usually indicates active HBV replication and risk of transmission of infection. In spite of the emerging use of chemiluminescence based quantitative HBsAg assays ...

Hepatocellular carcinoma and hepatitis B e antigen.

Hepatitis B e antigen serum persistence in an individual chronically infected with the Hepatitis B virus may be associated with a greatly increased risk of developing cirrhosis and hepatocellular carcinoma. This article presents an overview of the Hepatitis B e antigen and discusses the findings of a recent study evaluating its associated risk of hepatocellular carcinoma. A gross photographic i...